Research Interests

​Structural and functional characterization of MAP Kinase family proteins, which are responsible for plant immunity and stress tolerance.  I am particularly interested in MAP Kinase 4 from Arabidopsis, which plays a key role in Plant tolerance towards biotic and abiotic stress.  I will be using X-ray crystallography and other Biophysical techniques to study its interactions with other binding partners such as Proteins, DNA, etc and which will help me to understand the biological function of MAP Kinase 4 in transferring the information to other components in the cell, when it is stimulated by phosphorylation.

Selected Publications

  • Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokin...
    M. .Kitagawa, SY Fung, UF Hameed, H Goto, M. Inagaki, SH Lee
    Cell Reports, 7, 166-179, (2014)
  • Transcriptional Repressor Domain of MBD1 is Intrinsically Disordered and Interacts with its Binding Partners in a S...
    US Hameed, J. Lim, Q. Zhang, MA Wasik, D. Yang, K. Swaminathan.
    Scientific Reports, 4 : 4896, (2014)
  • An integrated structure- and system-based framework for identification of new targets for metabolites and known dru...
    H. Naveed, US Hameed, D. Harrus, W. Bourguet, ST. Arold, X. Gao.
    Bioinformatics, pii: btv477, (2015)

Education Profile

  • PhD (Structural Biology), National University of Singapore, Singapore, 2013
  • M.Tech (Medical Biotechnology), IIT Madras, Chennai, India 2008
  • B.Pharm, TN Dr. MGR Medical University, Chennai, India 2006

Professional Profile

  • 2013-current Post-doctoral fellow, KAUST, Thuwal, Saudi Arabia
  • 2008-2013 PhD Student in National University of Singapore, Singapore