The Genome of Chenopodium Quinoa

D.E. Jarvis, Y.S. Ho, D.J. Lightfoot, S.M. Schmöckel, B. Li, T.J. A. Borm, H. Ohyanagi, K. Mineta, C.T. Michell, N Saber, N.M. Kharbatia, R.R. Rupper, A.R. Sharp, N Dally, B. A. Boughton, Y.H. Woo, G. Gao, E.G. W. M. Schijlen, X. Guo, A.A. Momin........
Nature 542(7641), 307-312, (2017)

The Genome of Chenopodium Quinoa

Keywords

Genome, Chenopodium, Quinoa

Abstract

Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.



Authors:

D.E. Jarvis, Y.S. Ho, D.J. Lightfoot, S.M. Schmöckel, B. Li, T.J. A. Borm, H. Ohyanagi, K. Mineta, C.T. Michell, N Saber, N.M. Kharbatia, R.R. Rupper, A.R. Sharp, N Dally, B. A. Boughton, Y.H. Woo, G. Gao, E.G. W. M. Schijlen, X. Guo, A.A. Momin, S. Negrão, S. Al-Babili, C. Gehring, U. Roessner, C. Jung, K. Murphy, S.T. Arold, T. Gojobori, C.G. Linden, E.N. van Loo, E.N. Jellen, P.J. Maughan, M. Tester


Code

DOI: 10.1038/nature21370

Sources

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