Research Interests

​Prof. Arold's research is dedicated to elucidating the molecular basis of the function and (de)regulation of proteins central to cellular key signaling networks in bacteria, plants, and animals. His investigations are based on an integrated structural biology approach that combines functional and structural data from multiple sources (small angle x-ray scattering, X-ray crystallography, NMR, EM, computational methods, biochemistry, ligand binding assays and functional analyses). Results are translated to engineer molecules with desired properties  (e.g. reporters or inhibitors). Structural biology approaches are also used to enhance computational methods for functional annotation of genes (system-wide or focused).


Selected Publications


Education Profile

  • ​2004   Habilitation. University of Montpellier I, France

  • 1998    PhD degree 'European Label' (passed with distinction 'cum laude'). University of Montpellier I, France

  • 1995   D.E.A. (5th year of studies) in Molecular Biophysics and Molecular Biology (ranked major of group). University               of  Montpellier I, France       

  • 1994    Master degree (4th year of studies) in Physics. Joseph Fourier University, Grenoble, France

  • 1992    Vordiplom (second year diploma) in Physics, passed with best distinction ("sehr gut"). Unviversity of Würzburg, Germany


Professional Profile

  • 2013 – date     Associate Professor of Bioscience, KAUST, Saudi Arabia

  • 2009 – 2013    Sabbatical (faculty appointment), MD Anderson Cancer Center (MDACC), Houston, USA

  • 2006 – date     Tenured Associate Professor (CR1) in the French governmental CNRS, Centre de Biochimie Structurale (CBS), Montpellier, France

  • 2001 – 2006    Tenured Assistant Professor (CR2) CNRS, CBS, Montpellier, France

  • 1998 - 2001    Postdoctoral fellow, Laboratory of Molecular Biophysics, Oxford, UK (Structural Biology, Biophysics, Biochemistry)


Scientific and Professional Memberships

  • ​Biochemical Society